Economy activities related to energy are among the main ones in the municipality. They are located in Valle de Escombreras. This spot, which is a valley, is located in a district named Escombreras that is placed in the south of the municipality and of 5–10 km from the main locality by its west. Agriculture is another noteworthy activity in Cartagena and 37.9% of the territory consisted of crop lands in 2017. The most widely grown products are melons, lettuces, potatoes, lemons and almonds. 52.77% of the agreements occurred in this sector and 42.83% of the workers were hired as labourers in 2012.[80] Shipbuilding has less weight than some centuries ago, but it is still moderately important. This is performed in the port of Cartagena, the main locality of the municipality. Plastic production is also performed, specifically in the northwest of the territory. The tertiary sector has risen during the last decades, specifically tourism and hotel industry. 14,12% of the agreements in the municipality were aimed at waiters in 2012.
Thanks to its strategic position on the Mediterranean, Cartagena has been inhabited by many different cultures, which have left their mark on its rich cultural heritage during a glorious and turbulent history.
The “Cartagena, Port of Cultures” initiative was created to allow visitors to enjoy a wide range of activities and visits, discovering the cultural wealth and rich history of the city. It is one of several projects to energize the tourist possibilities of this potential major cultural destination, frequently neglected by the mass-tourism, due to the proximity of several holiday resorts, and the refinery and other industrial development, which gave a bad reputation to the city because of pollution; these last have now fortunately been eradicated.